Arnfinn Sundsfjord
Bjørg Haldorsen,
Ørjan Samuelsen,
Jessin Janice,
Miriam Sare,
Mari Molvik,
Arnfinn Sundsfjord
m.fl.:
Import of global high-risk clones is the primary driver of carbapenemase-producing Pseudomonas aeruginosa in Norway
Journal of Medical Microbiology 2025
Hege Harboe-Sjåvik,
Kristoffer Endresen,
Sandra Elena Ã…sheim,
Arnfinn Ståle Sundsfjord
:
FilmArray (BCID2) provides essential and timely results in bloodstream infections in small acute care hospitals without conventional microbiology services
APMIS - Journal of Pathologiy, Microbiology and Immunology 2024 /
Silvia Bertagnolio,
Zlatina Dobreva,
Chad M Centner,
Ioana Diana Olaru,
Daniele Donà ,
Stefano Burzo
m.fl.:
WHO global research priorities for antimicrobial resistance in human health
Lancet Microbe 2024 /
Kara K. Tsang,
Margaret M C Lam,
Ryan R. Wick,
Kelly L. Wyres,
Michael Bachman,
Stephen Baker
m.fl.:
Diversity, functional classification and genotyping of SHV β-lactamases in Klebsiella pneumoniae
Microbial Genomics 2024 /
Aasmund Fostervold,
Niclas Peter Raffelsberger,
Marit Hetland,
Ragna-Johanne Bakksjø,
Eva Bernhoff,
Ørjan Samuelsen
m.fl.:
Risk of death in Klebsiella pneumoniae bloodstream infections is associated with specific phylogenetic lineages
Journal of Infection 2024 /
Kristin Hegstad,
Anna Kaarina Pöntinen,
Jørgen Bjørnholt,
Else Quist Paulsen,
Arnfinn Ståle Sundsfjord
:
The first tigecycline resistant Enterococcus faecium in Norway was related to tigecycline exposure
Journal of Global Antimicrobial Resistance 2023 /
Mushtaq Talib Shawi al Rubaye,
Jessin Janice,
Jørgen Bjørnholt,
Iren Høyland Löhr,
Arnfinn Ståle Sundsfjord,
Kristin Hegstad
:
The first vanE-type vancomycin resistant Enterococcus faecalis isolates in Norway – phenotypic and molecular characteristics
Journal of Global Antimicrobial Resistance 2023 /
Mushtaq al Rubaye,
Jessin Janice,
Jørgen Vildershøj Bjørnholt,
Oliver Kacelnik,
Bjørg C. Haldorsen,
Randi M. Nygaard
m.fl.:
The population structure of vancomycin-resistant and
-susceptible Enterococcus faecium in a low-prevalence
antimicrobial resistance setting is highly influenced by
circulating global hospital-associated clones
Microbial Genomics 2023 / /
Marit Hetland,
Jane Hawkey,
Eva Bernhoff,
Ragna-Johanne Bakksjø,
HÃ¥kon Kaspersen,
Siren Rettedal
m.fl.:
Within-patient and global evolutionary dynamics of Klebsiella pneumoniae ST17
Microbial Genomics 2023 /
Theresa Wagner,
Jessin Janice,
Marc Schluz,
Susan Ballard,
Anders da Silva,
Geoffrey W Coombs
m.fl.:
Reversible vancomycin susceptibility within emerging ST1421 Enterococcus faecium strains is associated with rearranged vanA-gene clusters and increased vanA plasmid copy number
International Journal of Antimicrobial Agents 2023 /
Tore Taksdal Stubhaug,
Christian G. Giske,
Ulrik S Justesen,
Gunnar Kahlmeter,
Erika Matuschek,
Arnfinn Sundsfjord
m.fl.:
Antimicrobial susceptibility testing of Bacteroides species by disk diffusion: The NordicAST Bacteroides study
Anaerobe 2023 /
Theresa Wagner,
Benjamin P Howden,
Arnfinn Sundsfjord,
Kristin Hegstad
:
Transiently silent acquired antimicrobial resistance: an emerging challenge in susceptibility testing
Journal of Antimicrobial Chemotherapy 2023 /
Paul Christoffer Lindemann,
Torunn Pedersen,
Dorthea Hagen Oma,
Jessin Janice,
Fredrik Grøvan,
Ghantous Milad Chedid
m.fl.:
Intraregional hospital outbreak of OXA-244-producing Escherichia coli ST38 in Norway, 2020
Eurosurveillance 2023 /
Oskar Ljungquist,
Bjørg Haldorsen,
Anna Kaarina Pöntinen,
Jessin Janice,
Ellen Haldis Josefsen,
Petter Elstrøm
m.fl.:
Nationwide, population-based observational study of the molecular epidemiology and temporal trend of carbapenemase-producing Enterobacterales in Norway, 2015 to 2021
Eurosurveillance 06. juli 2023 / /
Niclas Peter Raffelsberger,
Dorota Julia Buczek,
Kristian Svendsen,
Lars Småbrekke,
Anna Kaarina Pöntinen,
Iren Høyland Löhr
m.fl.:
Community carriage of ESBL-producing Escherichia coli and Klebsiella pneumoniae: a cross-sectional study of risk factors and comparative genomics of carriage and clinical isolates
mSphere 2023 /
Kenneth Lindstedt,
Dorota Julia Buczek,
Torunn Annie Pedersen,
Erik Hjerde,
Niclas Peter Raffelsberger,
Yutaka Suzuki
m.fl.:
Detection of Klebsiella pneumoniae human gut carriage: a comparison of culture, qPCR, and whole metagenomic sequencing methods
Gut microbes 31. august 2022 /
Faheema Ebrahim Choonara,
Bjørg Haldorsen,
Jessin Janice,
Joshua Mbanga,
Isaac Ndhlovu,
Osborne Saulosi
m.fl.:
Molecular Epidemiological Characterisation of ESBL- and Plasmid-Mediated AmpC-Producing Escherichia coli and Klebsiella pneumoniae at Kamuzu Central Hospital, Lilongwe, Malawi
Tropical Medicine and Infectious Disease 2022 /
Kirsten Midttun Gravningen,
Oliver Kacelnik,
Egil Lingaas,
Torunn Pedersen,
Bjørn Gunnar Iversen,
Anne Mette Asfeldt
m.fl.:
Pseudomonas aeruginosa countrywide outbreak in hospitals linked to pre-moistened non-sterile washcloths, Norway, October 2021 to April 2022
Eurosurveillance 2022 /
Caillan Crowe-McAuliffe,
Victoriia Murina,
Kathryn Jane Turnbull,
Susanne Huch,
Marje Kasari,
Hiraku Takada
m.fl.:
Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics
Nature Communications 2022 /
Faheema E. Choonara,
Bjørg Haldorsen,
Isaac Ndhlovu,
Osborne Saulosi,
Tarsizio Maida,
Fanuel Lampiao
m.fl.:
Antimicrobial susceptibility profiles of clinically important bacterial pathogens at the Kamuzu Central Hospital in Lilongwe, Malawi
Malawi Medical Journal 2022 /
Jessin Janice,
Nicholas Agyepong,
Alex Owusu-Ofori,
Usha Govinden,
Sabiha Essack,
Ørjan Samuelsen
m.fl.:
Carbapenem resistance determinants acquired through novel chromosomal integrations in extensively drug-resistant pseudomonas aeruginosa
Antimicrobial Agents and Chemotherapy 2021 /
Niclas Peter Raffelsberger,
Marit Andrea Klokkhammer Hetland,
Kristian Svendsen,
Lars Småbrekke,
Iren Høyland Löhr,
Lotte Andreassen
m.fl.:
Gastrointestinal carriage of Klebsiella pneumoniae in a general adult population: a cross-sectional study of risk factors and bacterial genomic diversity
Gut microbes 2021 /
Abel F.N.D. Phiri,
Akebe Luther King Abia,
Daniel Gyamfi Amoako,
Rajab Mkakosya,
Arnfinn Sundsfjord,
Sabiha Essack
m.fl.:
Burden, antibiotic resistance, and clonality of shigella spp. Implicated in community-acquired acute diarrhoea in Lilongwe, Malawi
Tropical Medicine and Infectious Disease 2021 /
Marit Østlyngen Riibe,
Sveinung Wergeland Sørbye,
Gunnar Skov Simonsen,
Arnfinn Sundsfjord,
Josef Ekgren,
Jan Martin Maltau
:
Risk of cervical intraepithelial neoplasia grade 3 or higher (CIN3+) among women with HPV-test in 1990–1992, a 30-year follow-up study
Infectious Agents and Cancer 2021 /
Mushtaq T.S. Al-Rubaye,
Jessin Janice,
Jørgen Vildershøj Bjørnholt,
Aleksandra Jakovljev,
Maria Elisabeth Hultström,
Arnfinn Sundsfjord
m.fl.:
Novel genomic islands and a new vanD-subtype in the first sporadic VanD-type vancomycin resistant enterococci in Norway
PLOS ONE 2021 /
Calvina Estalva,
Tomas Zimba,
Sekyere John,
Usha Govinden,
Hafizah Y. Chenia,
Gunnar Skov Simonsen
m.fl.:
High prevalence of multidrug resistant ESBL- and plasmid mediated AmpC-producing clinical isolates of Escherichia coli at Maputo Central Hospital, Mozambique
BMC Infectious Diseases 2021 /
Aasmund Fostervold,
Marit Andrea Klokkhammer Hetland,
Ragna-Johanne Bakksjø,
Eva Bernhoff,
Kathryn E. Holt,
Ørjan Samuelsen
m.fl.:
A nationwide genomic study of clinical Klebsiella pneumoniae in
Norway 2001–15: introduction and spread of ESBLs facilitated by
clonal groups CG15 and CG307
Journal of Antimicrobial Chemotherapy 2021 /
Veronika Vorobieva,
Anne-Sofie Furberg,
Hans-Christian Slotved,
Tatiana Bazhukova,
Bjørg Haldorsen,
Dominique A Caugant
m.fl.:
Epidemiological and molecular characterization of Streptococcus pneumoniae carriage strains in pre-school children in Arkhangelsk, northern European Russia, prior to the introduction of conjugate pneumococcal vaccines
BMC Infectious Diseases 2020 / /
Sara Lino Faife,
Tomas Zimba,
John Osei Sekyere,
Usha Govinden,
Hafizah Y. Chenia,
Gunnar Skov Simonsen
m.fl.:
β-lactam and fluoroquinolone resistance in Enterobacteriaceae from imported and locally-produced chicken in Mozambique
Journal of Infection in Developing Countries 2020 /
Fredrik HÃ¥konsholm,
Marit Andrea Klokkhammer Hetland,
Cecilie Smith Svanevik,
Arnfinn Sundsfjord,
Bjørn Tore Lunestad,
Nachiket Marathe
:
Antibiotic sensitivity screening of Klebsiella spp. and Raoultella spp. isolated from marine bivalve molluscs reveal presence of CTX-M-producing K. pneumoniae
Microorganisms 30. november 2020 /
Theresa Wagner,
Jessin Janice,
Audun Sivertsen,
Ingegerd Sjögren,
Arnfinn Sundsfjord,
Kristin Hegstad
:
Alternative vanHAX promoters and increased vanA-plasmid copy number resurrect silenced glycopeptide resistance in Enterococcus faecium
Journal of Antimicrobial Chemotherapy 2020 /
Ilya Nikolaevich Zykov,
Niels Frimodt-Møller,
Lars Småbrekke,
Arnfinn Sundsfjord,
Ørjan Samuelsen
:
Efficacy of mecillinam against clinical multidrug-resistant Escherichia coli in a murine urinary tract infection model
International Journal of Antimicrobial Agents 02. november 2019 /
Alison Holmes,
Mark Holmes,
Thomas Gottlieb,
Lance B Price,
Arnfinn Sundsfjord
:
End non-essential use of antimicrobials in livestock
The BMJ 2019
Nicholas Agyepong,
Usha Govinden,
Alex Owusu-Ofori,
Daniel Gyamfi Amoako,
Mushal Allam,
Jessin Janice James Peter
m.fl.:
Genomic characterization of multidrug-resistant ESBL-producing Klebsiella pneumoniae isolated from a Ghanaian teaching hospital
International Journal of Infectious Diseases 2019 /
Maria Mellemstrand Grønmo,
Janne Møller-Stray,
Per Espen Akselsen,
Paul Christoffer Lindemann,
Aasmund Fostervold,
Caroline Vestby Knudsen
m.fl.:
Gentamicin bør fortsatt inngå i empirisk sepsisregime hos voksne
Tidsskrift for Den norske legeforening (Tidsskriftet) 2024 /
Miriam Sare,
Ørjan Samuelsen,
Niclas Peter Raffelsberger,
Arnfinn Ståle Sundsfjord,
Iren Høyland Löhr,
Aasmund Fostervold
m.fl.:
Risikovurdering av hypervirulente Klebsiella pneumoniae i Norge : en norsk risikovurdering av ECDC sin Rapid Risk Assessment "Emergence of hypervirulent Klebsiella pneumoniae ST23 carrying carbapenemase genes in EU/EEA countries, first update"
Folkehelseinstituttet 2024
Theresa Maria Wagner,
Anna Kaarina Pöntinen,
Mushtaq T.S. AL Rubaye,
Arnfinn Ståle Sundsfjord,
Kristin Hegstad
:
Adaptive cell wall thickening in Enterococcus faecalis is associated with decreased vancomycin susceptibility
Clinical Microbiology and Infection (CMI) 2023
Marit Hetland,
Mia Angelique Winkler,
Thomas D Stanton,
Ryan R. Wick,
Margaret MC Lam,
Aasmund Fostervold
m.fl.:
Klebsiella pneumoniae ecology and antimicrobial resistance in a One Health perspective
2023
Fredrik HÃ¥konsholm,
Arnfinn Sundsfjord,
Cecilie Smith Svanevik,
Bjørn Tore Lunestad,
Nachiket Marathe
:
Klebsiella pneumoniae in the marine setting – a challenge for seafood safety?
2023
Morten Lindbæk,
Arnfinn Ståle Sundsfjord
:
Improving antibiotic prescribing for uncomplicated UTIs
The BMJ 2023
Marit Hetland,
Jane Hawkey,
Eva Bernhoff,
Ragna-Johanne Bakksjø,
HÃ¥kon Kaspersen,
Siren Rettedal
m.fl.:
Within-patient and global evolutionary dynamics of Klebsiella pneumoniae ST17
2022
Klara Stensvåg,
Arnfinn Sundsfjord,
PÃ¥l Jarle Johnsen,
Hanna-Kirsti S. Leiros,
Lise Nordgård
:
CANS - Centre for New Antibacterial Strategies
2022 PROSJEKT
Bjørg C Haldorsen,
Erika Matuschek,
Jenny Ã…hman,
Gunnar Kahlmeter,
Arnfinn Sundsfjord,
Kristin Hegstad
:
Performance of the EUCAST disc diffusion method and gradient tests in detection of linezolid susceptibility in Enterococcus faecalis and Enterococcus faecium
2021
Yngvild Wasteson,
Henning Sørum,
Bjørn-Arne Lindstedt,
Adriana Dorota Osinska,
Arnfinn Sundsfjord,
Hans Geir Eiken
m.fl.:
CORNELIA – Antimicrobial Resistance (AMR) in One Health Interfaces
2021
Theresa Wagner,
Jessin Janice James Peter,
Marc Schulz,
Susan A. Ballard,
Anders Goncalves da Silva,
Geoffrey W Coombs
m.fl.:
Australian vancomycin variable E. faecium ST1421 revert to resistance by the use of an alternative vanHAX promoter and increased vanA-plasmid copy number
2021
Theresa Wagner,
Jessin Janice,
Audun Sivertsen,
Ingegerd Sjögren,
Arnfinn Sundsfjord,
Kristin Hegstad
:
The bag of tricks of vancomycin variable enterococci:
an alternative constitutive vanHAX-promoter, varying copy numbers and transferable resistance
2019
Lyn Middleton,
F Lampiao,
Tomas F. Zimba,
SM Muzime,
Gunnar Skov Simonsen,
Lars Småbrekke
m.fl.:
Sharing Knowledge Transforming Societies. The Norhed Programme 2013-2020
African Minds 2019
Jessin Janice James Peter,
Joachim Hegstad,
Ellen H. Josefsen,
Arnfinn Sundsfjord,
Kristin Hegstad
:
Increased prevalence of linezolid resistance mong clinical enterococci in Norway mainly due to spread of optrA E. faecalis
2019
A Basic,
Erika Matuschek,
O Karatuna,
Bjørg C Haldorsen,
Kristin Hegstad,
Jenny Ã…hman
m.fl.:
Evaluation of gradient tests for vancomycin MIC determination in Enterococcus faecalis and Enterococcus faecium. Effect of incubation for 16-20 hours vs. 24 hours
2019
Paul Christoffer Lindemann,
Karianne Wiger Gammelsrud,
Iren Høyland Löhr,
Per Espen Akselsen,
Morten Lindbæk,
Arnfinn Sundsfjord
:
Valg av antibiotika - viktig endring i prøvesvar fra mikrobiologen
Tidsskrift for Den norske legeforening (Tidsskriftet) 2019
Forskningsinteresser
- Antibiotika, antibiotikaresistente bakterier og evolusjon
- Klebsiella pneumoniae (Kp) er en sentral aktør i den globale spredningen av antibiotikaresistens. Våre studier involverer komparative molekylære epidemiologiske studier (helgenomsekvensering og metagenomikk) av Kp fra ulike økologiske nisjer inkludert mennesker og dyr, feno- og genotypiske assosiasjoner i patogenitet og antibiotikaresistens (genomassosiasjonsstudier og maskinlæring), samt prekliniske effekstudier av bakterievirus (bakteriofager) evne til å fjerne bærerskap eller infeksjoner med multiresistente Kp. Kp-studiene er finansiert av Trond Mohn Stiftelsen ( https://mohnfoundation.no/amr-prosjekter/) og partnerinstitusjoner.
- Leder for Senter for nye antibakterielle strategier (CANS; /research/cans): Et tverrfaglig forskningssenter finansiert av ÐÒÔË´óתÅÌ og Tromsø Forskningsstiftelse (https://tfstiftelse.no/) 2019 -.
- Seksjonsoverlege, Nasjonal kompetansetjeneste for påvisning av antibiotikaresistens (K-res; https://unn.no/fag-og-forskning/k-res) ved Universitetssykehuset Nord-Norge (UNN) finansiert av Helse- og omsorgsdepartementet, Helse Nord RHF og UNN.
Medlem i forskningsgruppe
CV
Utdanning:
1983: Cand.med (MD) Universitetet i Tromsø
1991: Spesialist i Medisinsk mikrobiologi
1994: Dr.med (PhD) Universitetet i Tromsø
2000-01: Visiting Professor Institutt Pasteur, Paris
Yrkespraksis:
1983-95: Turnus-/militærlege. Assistent-/overlege Medisinsk mikrobiologi, Universitetssykehuset i Nord-Norge
1987-90: Stipendiat, Den Norske Kreftforening, v/ÐÒÔË´óתÅÌ
1995-96: Avdelingsoverlege Mikrobiologisk avdeling, UNN
1995 - : Førsteamanuensis/Professor Medisinsk mikrobiologi, ÐÒÔË´óתÅÌ
1996-00: Nestleder/Leder for studiestyret medisin, ÐÒÔË´óתÅÌ
2005-09: Prodekan forskning, Det Medisinske fakultet, ÐÒÔË´óתÅÌ
2009 - 17 : Dekan, Det helsevitenskapelige fakultet, ÐÒÔË´óתÅÌ
Vedlegg:
- 20-01-16 CV_AS (pdf)