Bjørn Olav Brandsdal
Ryan Scott Wilkins,
Bjarte Aarmo Lund,
Geir Villy Isaksen,
Johan Lennart G枚sta 脜qvist,
Bj酶rn Olav Brandsdal
:
Accurate Computation of Thermodynamic Activation Parameters in the Chorismate Mutase Reaction from Empirical Valence Bond Simulations
Journal of Chemical Theory and Computation 2024 /
Florian van der Ent,
Susann Skagseth,
Bjarte Aarmo Lund,
Jaka So膷an,
Julia J. Griese,
Bj酶rn Olav Brandsdal
m.fl.:
Computational design of the temperature optimum of an enzyme reaction
Science Advances 2023 /
Philip Ben Rainsford,
Birta R. Sarre,
Margherita Falavigna,
Bj酶rn Olav Brandsdal,
G酶ril Eide Flaten,
Martin Jakubec
m.fl.:
WIND-PVPA: Water/Ion NMR Detected PVPA to assess lipid barrier integrity in vitro through quantification of passive water- and ion transport
Biochimica et Biophysica Acta - Biomembranes 2022 /
Florian van der Ent,
Bjarte Aarmo Lund,
Linn Svalberg,
Miha Purg,
Ghislean Chukwu,
Mikael Widersten
m.fl.:
Structure and Mechanism of a Cold-Adapted Bacterial Lipase
Biochemistry 2022 /
Bjarte Aarmo Lund,
Bj酶rn Olav Brandsdal
:
ThermoSlope: A Software for Determining Thermodynamic Parameters from Single Steady-State Experiments
Molecules 2021 /
Jaka Socan,
Geir Villy Isaksen,
Bj酶rn Olav Brandsdal,
Johan Lennart G枚sta 脜qvist
:
Towards Rational Computational Engineering of Psychrophilic Enzymes
Scientific Reports 2019 /
Willem Jespers,
Geir Villy Isaksen,
Tor Arne Heim Andberg,
Silvana Vasile,
Amber van Veen,
Johan 脜qvist
m.fl.:
QresFEP: An Automated Protocol for Free Energy Calculations of Protein Mutations in Q
Journal of Chemical Theory and Computation 2019 /
Jaka Socan,
Masoud Kazemi,
Geir Villy Isaksen,
Bj酶rn Olav Brandsdal,
Johan 脜qvist
:
Catalytic Adaptation of Psychrophilic Elastase
Biochemistry 2018
Davide Michetti,
Bj酶rn Olav Brandsdal,
Davide Bon,
Geir Villy Isaksen,
Matteo Tiberti,
Elena Papaleo
:
A comparative study of cold-and warmadapted Endonucleases A using sequence analyses and molecular Dynamics simulations
PLOS ONE 2017 /
Marthe M氓l酶y,
Frode M氓l酶y,
Per Jakobsen,
Bj酶rn Olav Brandsdal
:
Dynamic self-organisation of haematopoiesis and (a)symmetric cell division
Journal of Theoretical Biology 2017 /
Johan 脜qvist,
Masoud Kazemi,
Geir Villy Isaksen,
Bj酶rn Olav Brandsdal
:
Entropy and Enzyme Catalysis
Accounts of Chemical Research 2017 /
Johan 脜qvist,
Geir Villy Isaksen,
Bj酶rn Olav Brandsdal
:
Computation of enzyme cold adaptation
Nature Reviews Chemistry 2017
Geir Villy Isaksen,
Johan 脜qvist,
Bj酶rn Olav Brandsdal
:
Thermodynamics of the Purine Nucleoside Phosphorylase Reaction Revealed by Computer Simulations
Biochemistry 2017
Ulli Rothweiler,
Wenche Stensen,
Bj酶rn Olav Brandsdal,
Johan Isaksson,
Frederick Alan Leeson,
Richard Alan Engh
m.fl.:
Probing the ATP-Binding Pocket of Protein Kinase DYRK1A with Benzothiazole Fragment Molecules
Journal of Medicinal Chemistry 2016
Geir Villy Isaksen,
Johan 脜qvist,
Bj酶rn Olav Brandsdal
:
Enzyme surface rigidity tunes the temperature dependence of catalytic rates
Proceedings of the National Academy of Sciences of the United States of America (PNAS) 12. juli 2016
Geir Villy Isaksen,
Kathrin Helen Hopmann,
Johan 脜qvist,
Bj酶rn Olav Brandsdal
:
Computer Simulations Reveal Substrate Specificity of Glycosidic Bond Cleavage in Native and Mutant Human Purine Nucleoside Phosphorylase
Biochemistry 17. mars 2016
Marte R酶rvik H酶yem,
Frode M氓l酶y,
Per Jakobsen,
Bj酶rn Olav Brandsdal
:
Stem cell regulation: Implications when differentiated cells regulate symmetric stem cell division
Journal of Theoretical Biology 2015 /
Geir Villy Isaksen,
Tor Arne Heim Andberg,
Johan 脜qvist,
Bj酶rn Olav Brandsdal
:
Qgui: A high-throughput interface for automated setup and analysis of free energy calculations and empirical valence bond simulations in biological systems
Journal of Molecular Graphics and Modelling 2015
Geir Villy Isaksen,
Johan 脜qvist,
Bj酶rn Olav Brandsdal
:
Protein surface softness is the origin of enzyme cold-adaptation of trypsin
PLoS Computational Biology 2014 /
Annfrid Sivertsen,
Johan Isaksson,
Hanna-Kirsti S. Leiros,
Johan Svenson,
John Sigurd Svendsen,
Bj酶rn Olav Brandsdal
:
Synthetic cationic antimicrobial peptides bind with their hydrophobic parts to drug site II of human serum albumin
BMC Structural Biology 2014 /
Annfrid Sivertsen,
Veronika T酶rfoss,
Johan Isaksson,
Dominik Ausbacher,
Trude Anderssen,
Bj酶rn Olav Brandsdal
m.fl.:
Anticancer potency of small linear and cyclic tetrapeptides and pharmacokinetic investigations of peptide binding to human serum albumin
Journal of Peptide Science 2014
Annfrid Sivertsen,
Bj酶rn Olav Brandsdal,
John Sigurd Svendsen,
Jeanette hammer Andersen,
Johan Svenson
:
Short cationic antimicrobial peptides bind to human alpha-1 acid glycoprotein with no implications for the in vitro bioactivity
Journal of Molecular Recognition 2013
Rianne Harmsen,
Annfrid Sivertsen,
Davide Michetti,
Bj酶rn Olav Brandsdal,
Leiv K. Sydnes,
Bengt Erik Haug
:
Synthesis and docking of novel piperidine renin inhibitors
Monatshefte f眉r Chemie 2013
Maarten Beerepoot,
Arnfinn Hykkerud Steindal,
Jacob Kongsted,
Bj酶rn Olav Brandsdal,
Luca Frediani,
Kenneth Ruud
:
A polarizable embedding DFT study of one-photon absorption in fluorescent proteins
Physical Chemistry, Chemical Physics - PCCP 2013
Veronika T酶rfoss,
Dominik Ausbacher,
Cristiane de Albuquerque Cavalcanti Jacobsen,
Terkel Hansen,
Bj酶rn Olav Brandsdal,
Martina Havelkova
m.fl.:
Synthesis of anticancer heptapeptides containing a unique lipophilic 尾2,2-amino acid building block
Journal of Peptide Science 2012
Rasmus T酶rnes Karstad,
Geir Villy Isaksen,
Evelien Wynendaele,
Yngve Guttormsen,
Bart De Spiegeleer,
Bj酶rn Olav Brandsdal
m.fl.:
Targeting the S1 and S3 Subsite of Trypsin with Unnatural Cationic Amino Acids Generates Antimicrobial Peptides with Potential for Oral Administration
Journal of Medicinal Chemistry 2012
Hanna-Kirsti S. Leiros,
Naga Pardha Saradhi Borra,
Bj酶rn Olav Brandsdal,
Kine Susann Waade Edvardsen,
James Spencer,
Timothy R. Walsh
m.fl.:
Crystal Structure of the Mobile Metallo-beta-Lactamase AIM-1 from Pseudomonas aeruginosa: Insights into Antibiotic Binding and the Role of Gln157
Antimicrobial Agents and Chemotherapy 2012
Veronika T酶rfoss,
Johan Isaksson,
Dominik Ausbacher,
Bj酶rn Olav Brandsdal,
G酶ril Eide Flaten,
Trude Anderssen
m.fl.:
Improved anticancer potency by head-to-tail cyclization of short cationic anticancer peptides containing a lipophilic b2,2-amino acid
Journal of Peptide Science 2012
Johan Isaksson,
Bj酶rn Olav Brandsdal,
Stig Olov Magnus Engqvist,
G酶ril Eide Flaten,
John Sigurd Svendsen,
Wenche Stensen
:
A Synthetic Antimicrobial Peptidomimetic (LTX 109): Stereochemical Impact on Membrane Disruption
Journal of Medicinal Chemistry 2011
Peter Kyomuhendo,
Bj酶rnar Myrnes,
Bj酶rn Olav Brandsdal,
Arne Smal氓s,
Inge Waller Nilsen,
Ronny Helland
:
Thermodynamics and structure of a salmon cold active goose-type lysozyme
Comparative Biochemistry and Physiology - Part B: Biochemistry & Molecular Biology 2010
Bj酶rn Olav Brandsdal
:
Kuledetilpassninger - livet under og rundt vannets frysepunkt
2019
Bj酶rn Olav Brandsdal
:
Multiphase system
2019
Bj酶rn Olav Brandsdal
:
Computation of enzyme cold-adaptation
2019
Karolina Solheimslid Eik氓s,
Kenneth Ruud,
Maarten Beerepoot,
Bj酶rn Olav Brandsdal
:
Towards a computational protocol for VCD spectra of cyclic peptides
2019
Karolina Solheimslid Eik氓s,
Kenneth Ruud,
Maarten Beerepoot,
Bj酶rn Olav Brandsdal
:
Towards a computational protocol for VCD spectra of cyclic peptides
2019
Karolina Solheimslid Eik氓s,
Kenneth Ruud,
Maarten Beerepoot,
Bj酶rn Olav Brandsdal
:
Towards a computational protocol for VCD spectra of cyclic peptides
2019
Karolina Solheimslid Eik氓s,
Kenneth Ruud,
Maarten Beerepoot,
Bj酶rn Olav Brandsdal
:
Towards a computational protocol for VCD spectra of cyclic peptides
2019
Bj酶rn Olav Brandsdal
:
Computer simulations of cold-adaptation
2019
Bj酶rn Olav Brandsdal
:
Computation of enzyme cold-adaptation II
2019
Geir Villy Isaksen,
Bj酶rn Olav Brandsdal
:
Troms酶 VR lab (forskningsdagene 2019)
Forskningsdagene 2019 2019
Geir Villy Isaksen,
Johan 脜qvist,
Bj酶rn Olav Brandsdal
:
Computation of Enzyme Temperature Adaptation - Protein Surface Softness Regulates the Enthalpy-Entropy Balance.
2018
Laura Liikanen,
Bj酶rn Olav Brandsdal
:
DigiBiotics
2018
Marc Boomgaren,
Birta Ravdna Sarre,
Tor Arne Heim Andberg,
Bj酶rn Olav Brandsdal,
Johan Isaksson,
J酶rn H Hansen
:
Synthesis and exploration of a novel molecular scaffold for dUTPase inhibition: Aiming for new anticancer agents
2017
B Sorensen,
MA Sommerfelt,
G Stjernholm,
PL Smith,
M Okvist,
Bj酶rn Olav Brandsdal
m.fl.:
The HIV-1 gp120 C5 Region Shows HLA-like Properties for Immune Activation that May Be Masked by Antibodies
AIDS Research and Human Retroviruses 2013
Bj酶rn Olav Brandsdal,
Kenneth Ruud,
Maarten Beerepoot,
Arnfinn Hykkerud Steindal
:
Datamodellering i kjemi og biologi, en selvmotsigelse?
Nordlys 09. desember 2013
Maarten Beerepoot,
Bj酶rn Olav Brandsdal,
Kenneth Ruud,
Arnfinn Hykkerud Steindal
:
Nobelprisen i kjemi 2013
Kjemi 2013
Rianne Harmsen,
Annfrid Sivertsen,
Davide Michetti,
Bj酶rn Olav Brandsdal,
Leiv K. Sydnes,
Bengt Erik Haug
:
Synthesis and docking of 4-triazolyl substituted piperidine derivatives as novel renin inhibitors
2012
Rianne Harmsen,
A Sivertsen,
Davide Michetti,
Bj酶rn Olav Brandsdal,
Leiv Kristen Sydnes,
Bengt Erik Haug
:
Synthesis and docking of 4-triazolyl substituted piperidine derivatives as novel renin inhibitors
Journal of Peptide Science 2012
Geir Villy Isaksen,
Johan Isaksson,
John Sigurd Svendsen,
Bj酶rn Olav Brandsdal
:
Structural studies of small cationic antimicrobial peptides by NMR and computer simulations have facilitated a refined pharmacophore model able to predict activity versus Staphylococcus aureus
2011
Geir Villy Isaksen,
Rasmus T酶rnes Karstad,
Johan Mattias Isaksson,
Johan Svenson,
John Sigurd Svendsen,
Bj酶rn Olav Brandsdal
:
Structure of short cationic antimicrobial peptides and their interactions with membranes as revealed by MD simulations
2010
