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  3. Ronny Helland
Bilde av Helland, Ronny
Bilde av Helland, Ronny
Kontorsjef Institutt for kjemi Institutt for kjemi ronny.helland@uit.no +4777646474 +47 90940431 Tromsø Her finner du meg

Ronny Helland

  • Scott Mazurkewich, Ronny Helland, Alasdair Mackenzie, Vincent Eijsink, Phillip Byron Pope, Gisela Br盲nd茅n m.fl.:
    Structural insights of the enzymes from the chitin utilization locus of Flavobacterium johnsoniae
    Scientific Reports 13. august 2020 /
  • Bjarni 脕sgeirsson, Sigurbj枚rn Mark煤sson, Sigr铆冒ur S. Hlynsd贸ttir, Ronny Helland, Jens G. Hj枚rleifsson :
    X-ray crystal structure of Vibrio alkaline phosphatase with the non-competitive inhibitor cyclohexylamine
    Biochemistry and Biophysics Reports 2020 /
  • Jens Gu冒mundur Hj枚rleifsson, Ronny Helland, Manuela Magnusdottir, Bjarni 脕sgeirsson :
    The high catalytic rate of the cold-active Vibrio alkaline phosphatase requires a hydrogen bonding network involving a large interface loop
    FEBS Open Bio 2020 /
  • Man Kumari Gurung, Bj酶rn Altermark, Ronny Helland, Arne O. Smal氓s, Inger Lin Uttakleiv R忙der :
    Features and structure of a cold active N-acetylneuraminate lyase
    PLOS ONE 2019 / /
  • Ronny Helland, Eva katrin Bj酶rkeng, Ulli Rothweiler, Magne Olav Sydnes, Daniela Maria Pampanin :
    The crystal structure of haemoglobin from Atlantic cod
    Acta Crystallographica. Section F : Structural Biology and Crystallization Communications 2019 /
  • Concetta De Santi, Osman A. B. S. M. Gani, Ronny Helland, Adele Kim Williamson :
    Structural insight into a CE15 esterase from the marine bacterial metagenome
    Scientific Reports 2017 /
  • Marit Seppola, Kathrine Ryvold Bakkemo, Helene V. Mikkelsen, Bj酶rnar Myrnes, Ronny Helland, David Irwin m.fl.:
    Multiple specialised goose-type lysozymes potentially compensate for an exceptional lack of chickentype lysozymes in Atlantic cod
    Scientific Reports 2016 / FULLTEKST /
  • Hilde Lysvand, Ronny Helland, Lars Hagen, Geir Slupphaug, Ole-Jan Iversen :
    Psoriasis pathogenesis 鈥 Pso p27 constitutes a compact structure forming large aggregates
    Biochemistry and Biophysics Reports 2015 /
  • Tony Christopeit, Trine Josefine Olsen Carlsen, Ronny Helland, Hanna-Kirsti S. Leiros :
    Discovery of novel inhibitor scaffolds against the metallo-尾-lactamase VIM-2 by surface plasmon resonance (SPR) based fragment screening
    Journal of Medicinal Chemistry 2015 /
  • Kenneth Johnson, Thomas Ve, 脴ivind Larsen, Rolf B. Pedersen, Johan R. Lillehaug, Harald B Jensen m.fl.:
    CorA is a copper repressible surface-associated copper(I)-binding protein produced in Methylomicrobium album BG8
    PLOS ONE 2014 /
  • Zarah Forsberg, Alasdair Mackenzie, Morten S酶rlie, 脜smund Kjendseth R酶hr, Ronny Helland, Andrew S. Arvai m.fl.:
    Structural and functional characterization of a conserved pair of bacterial cellulose-oxidizing lytic polysaccharide monooxygenases
    Proceedings of the National Academy of Sciences of the United States of America (PNAS) 28. april 2014
  • D. Cazamea-Catalan, E. Magnanou, Ronny Helland, L. Besseau, Gilles Boeuf, Jack Falc貌n m.fl.:
    Unique arylalkylamine N-acetyltransferase-2 polymorphism in salmonids and profound variations in thermal stability and catalytic efficiency conferred by two residues
    Journal of Experimental Biology 2013
  • Thomas Ve, Karina Mathisen, Ronny Helland, Odd Andre Karlsen, Anne Fjellbirkeland, 脜smund Kjendseth R酶hr m.fl.:
    The Methylococcus capsulatus (Bath) Secreted Protein, MopE*, Binds Both Reduced and Oxidized Copper
    PLOS ONE 2012 /
  • Leidy Lagos, Dimitar Borisov Iliev, Ronny Helland, Mario Rosemblatt, Jorunn B J酶rgensen :
    CD40L-A costimulatory molecule involved in the maturation of antigen presenting cells in Atlantic salmon (Salmo salar)
    Developmental and Comparative Immunology 2012
  • Damien D. Cazam猫a-Catalan, Elodie Magnanou, Ronny Helland, Gilmer Vanegas, Laurence Besseau, Gilles Boeuf m.fl.:
    Functional diversity of Teleost arylalkylamine N-acetyltransferase-2: is the timezyme evolution driven by habitat temperature?
    Molecular Ecology 2012
  • Peter Kyomuhendo, Bj酶rnar Myrnes, Bj酶rn Olav Brandsdal, Arne Smal氓s, Inge Waller Nilsen, Ronny Helland :
    Thermodynamics and structure of a salmon cold active goose-type lysozyme
    Comparative Biochemistry and Physiology - Part B: Biochemistry & Molecular Biology 2010
  • Ronny Helland, Renate Lie Larsen, Solrun Finstad, Peter Kyomuhendo, Atle Noralf Larsen :
    Crystal structures of g-type lysozyme from Atlantic cod shed new light on substrate binding and the catalytic mechanism
    Cellular and Molecular Life Sciences (CMLS) 2009
  • Anna Szlachcic, M Zakrzewska, D Krowarsch, vibeke Os, Ronny Helland, Arne Oskar Smal氓s m.fl.:
    Structure of a highly stable mutant of human fibroblast growth factor 1
    Acta Crystallographica Section D: Biological Crystallography 2009
  • Ronny Helland, Renate Lie Larsen, Bjarni 脜sgeirsson :
    The 1.4 angstrom crystal structure of the large and cold-active Vibrio sp. alkaline phosphatase
    Biochimica et Biophysica Acta - Proteins and Proteomics 2009
  • Bj酶rn Altermark, Ronny Helland, Elin Moe, Nils Peder Willassen, Arne Oskar Smal氓s :
    Structural adaptation of endonuclease I from the cold-adapted and halophilic bacterium Vibrio salmonicida
    Acta Crystallographica Section D: Biological Crystallography 2008
  • Bj酶rn Altermark, Ronny Helland, Elin Moe, Nils Peder Willassen, Arne Oskar Smal氓s :
    Environmental adaptation of endonuclease I from Vibrio salmonicida
    Acta Crystallographica Section D: Biological Crystallography 2008
  • Ronny Helland, Anne Fjellbirkeland, Odd-Arne Karlsen, Johan Richard Lillehaug, Harald Jensen, Thomas Ve :
    An oxidized tryptophan facilitates copper binding in Methylococcus capsulatus-secreted protein MopE
    Journal of Biological Chemistry 2008
  • Laila Mirja Niiranen, Bj酶rn Altermark, Bj酶rn Olav Brandsdal, Hanna-Kirsti S. Leiros, Ronny Helland, Arne Oskar Smal氓s m.fl.:
    Effects of salt on the kinetics and thermodynamic stability of endonuclease I from Vibrio salmonicida and Vibrio cholerae
    The FEBS Journal 2008
  • Ellen Kristin Riise, marit sjo Lorentzen, Ronny Helland, Arne Oskar Smal氓s, Hanna-Kirsti S. Leiros, Nils Peder Willassen :
    The first structure of a cold-active catalase from Vibrio salmonicida at 1.96 angstrom reveals structural aspects of cold adaptation
    Acta Crystallographica Section D: Biological Crystallography 2007
  • G Saelensminde, Gisle S忙lensminde, O Halskau, 脴yvind Halskau, Ronny Helland, Nils Peder Willassen m.fl.:
    Structure-dependent relationships between growth temperature of prokaryotes and the amino acid frequency in their proteins
    Extremophiles 2007
  • Ellen Kristin Riise, Marit Sjo Lorentzen, Ronny Helland, Nils P Willassen :
    Crystallization and preliminary X-ray diffraction analysis of a cold-adapted catalase from Vibrio salmonicida
    Acta Crystallographica. Section F : Structural Biology and Crystallization Communications 2006
  • Bj酶rn Altermark, Arne Oskar Smal氓s, Nils Peder Willassen, Ronny Helland :
    The structure of Vibrio cholerae extracellular endonuclease I reveals the presence of a buried chloride ion
    Acta Crystallographica Section D: Biological Crystallography 2006
  • Olayiwola Adekoya, Ronny Helland, Nils P Willassen, Ingebrigt Sylte :
    Comparative sequence and structure analysis reveal features of cold adaptation of an enzyme in the thermolysin family
    Proteins: Structure, Function, and Bioinformatics 2006
  • Ronny Helland, Atle Noralf Larsen, Arne Oskar Smal氓s, Nils Peder Willassen :
    The 1.8 angstrom crystal structure of a proteinase K-like enzyme from a psychrotroph Serratia species
    The FEBS Journal 2006
  • Atle Noralf Larsen, Elin Moe, Ronny Helland, Dag Rune Gjellesvik, Nils Peder Willassen :
    Characterization of a recombinantly expressed proteinase K-like enzyme from a psychrotrophic Serratia sp
    The FEBS Journal 2006
  • Honorata Czapinska, Ronny Helland, Arne Oskar Smal氓s, Jacek Otlewski :
    Crystal Structures of Five Bovine Chymotrypsin Complexes with P1 BPTI Variants
    Journal of Molecular Biology (JMB) 2004
  • Hanna-Kirsti S. Leiros, Hanna Kirsti Schr酶der Leiros, Bj酶rn Olav Brandsdal, Ole Andreas Andersen, vibeke Os, Ingar Leiros m.fl.:
    Trypsin specificity as elucidated by LIE calculations, X-ray structures, and association constant measurements
    Protein Science 2004
  • Man Kumari Gurung, Tor Olav Berg, Marie-Jos茅e Haglund Hals酶r, Bj酶rn Altermark, Ingar Leiros, Ronny Helland m.fl.:
    Efficient production of sialic acids- Using enzymes for biomass conversion
    2017
  • Man Kumari Gurung, Tor Olav Berg, Marie-Jos茅e Haglund Hals酶r, Bj酶rn Altermark, Ingar Leiros, Ronny Helland m.fl.:
    Efficient production of sialic acids- Using enzymes for biomass conversion
    2017
  • Tor Olav Berg, Bj酶rn Altermark, Ingar Leiros, Ronny Helland, Inger Lin Uttakleiv R忙der :
    Production of sialic acids and derivatives by enzyme catalysis
    2016
  • Tor Olav Berg, Marie-Jos茅e Haglund Hals酶r, Man Kumari Gurung, Bj酶rn Altermark, Ingar Leiros, Ulli Rothweiler m.fl.:
    From marine rest raw materials to sialic acids: Using enzymes for biomass conversion
    2016
  • Tor Olav Berg, Bj酶rn Altermark, Ingar Leiros, Ronny Helland, Inger Lin Uttakleiv R忙der :
    Biocatalytical production of sialic acids and derivatives
    2015
  • Yvonne Piotrowski, Netsanet Gizaw Assefa, Ronny Helland, Kirsti Merete Johannessen, Nils Peder Willassen, Atle Noralf Larsen :
    Enzymes from the Arctic - The cold gold
    2015
  • Inger Lin Uttakleiv R忙der, Bj酶rn Altermark, Man Kumari Gurung, Ronny Helland, Arne O. Smal氓s :
    Sialic acids in marine bacteria
    2014
  • Zarah Forsberg, Alasdair Mackenzie, Morten S酶rlie, 脜smund Kjendseth R酶hr, Ronny Helland, Gustav Vaaje-Kolstad m.fl.:
    Characterization of cellulose-active lytic polysaccharide monooxygenases with complementary activities
    2014
  • Yvonne Piotrowski, Netsanet Gizaw Assefa, Ronny Helland, Kirsti Merete Johannessen, Bjarne Landfald, Arne O. Smal氓s m.fl.:
    Enzymes from the Arctic - The cold gold
    2014
  • Inger Lin Uttakleiv R忙der, Man Kumari Gurung, Bj酶rn Altermark, Tor Olav Berg, Ronny Helland, Arne O. Smal氓s :
    Sialic acid biosynthesis in marine bacteria
    2013
  • Man Kumari Gurung, Bj酶rn Altermark, Inger Lin Uttakleiv R忙der, Ronny Helland, Arne O. Smal氓s :
    Features and structure of a sialic acid aldolase from Aliivibrio salmonicida
    2013
  • Odd-Arne Olsen, Wenche Johansen, Sidsel Emilsen, Tatiana Belova, Zhe Liang, Arne Smal氓s m.fl.:
    Structural & functional significance of the DEK1 phytocalpain during land plant evolution from green algae
    2010
  • Atle Noralf Larsen, Ronny Helland, Gunbj酶rg Svineng, Trond 脴. J酶rgensen :
    Identification, cloning and recombinant expression of a goose-type lysozyme from Atlantic cod (Gadus Morhua)
    2007
  • Bj酶rn Altermark, Ronny Helland, Laila Mirja Niiranen, Elin Moe, Bj酶rn Olav Brandsdal, Arne Oskar Smal氓s m.fl.:
    Optimum enzymatic activity of endonuclease I from Vibrio salmonicida and Vibrio cholerae correlateswith the bacterial growth habitat
    2006
  • Olayiwola Adedotun Adekoya, Ronny Helland, Nils Peder Willassen, Ingebrigt Sylte :
    Structural determinants for a cold adapted enzyme in the thermolysin family
    2005
  • Ronny Helland, Atle Noralf Larsen, Nils Peder Willassen :
    Structural basis for substrate specificity in two enzymes in the Proteinase K family
    2005
  • Atle Noralf Larsen, Ronny Helland, Dag Rune Gjellesvik, Nils Peder Willassen :
    Structural basis for S1-S4 specificity in two enzymes of the proteinase K family
    2004
  • Pirkko a Heikinheimo, Ronny Helland, Hanna-Kirsti S. Leiros, Ingar Leiros, Solveig Karlsen, gry Evjen m.fl.:
    Structure of the Bovine Lysosomal a-Mannosidase, the Enzyme Involved in the Lysosomal Storage Disease a-Mannosidosis
    ESRF Highlights 2002 2003

    • Forskningsinteresser

    Mine forskningsinteresser inkluderer struktur-funksjonsstudier av proteiner (enzymer): Hvordan påvirker den atomære strukturen enzymers aktivitet, spesifisitet og effektivitet. Enzymer med opprinnelse i kuldetilpassede organismer har ofte helt unike biokjemiske egenskaper, og disse ønsker man kunne anvende i biokjemisk og bioteknologisk industri.

    Deltakelse i prosjekter:


    Bacterial sialic acids

    Optimization and Application Development of Marine Cold-adapted DNA Polymerases – OptiZyme

    ORCID: 0000-0002-6271-1436