幸运大转盘

Bioinformatics is a combination of biological science and information technology used in analyzing and deriving conclusions from large data sets. This course introduces the students to microbial genomics and metagenomics. Genome-scale sequencing projects have led to an explosion of genetic information (gene sequences) available for analysis. The student will learn how these sequences can lead to a much fuller understanding of many biological processes.听

听The aim is to provide a theoretical introduction of the topics, tools and current trends in microbial genomics and metagenomics, followed by practical exercises using the methodology on Next generation sequence data.听Major听topics听will听include:听

• Bioinformatics听software听platforms听
• Genomics: quality control,听assembly听and annotation听
• Comparative听genomics听and听transcriptomics听
• Evolutionary听relationships and听genetic听diversity听
• Metagenomics,听amplicon听and听community听profiling听

Applicants from Nordic countries: 1st of December for the spring semester.

Applicants from outside the Nordic countries: 1st of October for the spring semester

Required: A bachelor鈥檚 degree in chemistry or biotechnology or equivalent, with a grade C or better in the Norwegian grading system.

Recommended: KJE-2004 or equivalent.

The student听has听acquired a solid and broad theoretical basis to understand bioinformatics.听This means that the student:听

Knowledge听

Bioinformatics听software听platforms听

• has knowledge about relevant software environments, including Linux,听Anaconda听and virtual machines.听
• can apply command line in Linux environments.听听听听
• can apply knowledge to choose software platform for manipulating raw next-generation sequence data听

Genomics: quality control,听assembly听and annotation听

• has knowledge about the principles behind quality assessment of genomics reads and sequences听
• has thorough knowledge about the basis different behind assembly methods and tools听
• can apply the knowledge to select tools for gene prediction and functional assignment of microbial genomes听

Comparative听genomics听and听transcriptomics听

• has advanced knowledge听tabout听underlying methods how two or more genomes can be aligned and compared.听
• has advanced knowledge for the basis behind transcriptomics (differential expressed genes) and analyze the results听

Evolutionary听relationships and听genetic听diversity听

• has advanced knowledge about principles behind phylogenetic and phylogenomic analyses听
• has thorough knowledge about software used for evolutionary studies听
• has advanced knowledge on the practical aspects of听analysing听genetic diversity听

Metagenomics,听amplicon听and听community听profiling听

• has an advanced knowledge about the different principles and methods used in community profiling听
• has advanced knowledge in analysis of microbial communities听

听

Skills听

• Can evaluate and select听bioinformatics tools and sequence data from听publically听available repositories, and use them to address biological听questions听
• Can use bioinformatic tools for analyzing genomes, transcriptomes, genetic variation, evolutionary听relationships听and microbial communities.听

听

General听competence 听 听

• can participate in discussions concerning microbial genomics and metagenomics with students, research fellows and the public.听
• has the ability to听plan and execute advanced bioinformatics tasks; processing and听analysing听microbial genomes, comparative genomic analyses, transcriptome analysis, infer phylogenetic relationships and genetic variations, and microbial community analysis.听
• can interpret, communicate and debate thoroughly on independent bioinformatics data and results.听
• can apply the knowledge to new research domains听
• Can use the acquired knowledge and carry out team assignments on new research topics by analyzing a given dataset.听
• Can effectively present aims, analysis methods,听results听and conclusions of a research project for research fellows and general public.听

Access to the examination requires completing the following course work requirements:听听

• Approval of eight out of ten submitted reports听

Examination:听

• Oral presentation of a group project counting 100%听
• Assessment听scale:听Pass/fail听

Students who fail the exam may register for a re-sit exam early in the following semester听

The date for the exam can be changed. The final date will be announced at your faculty early in May and early in November.